This sad little flower shop on Skid Rowe holds a secret.

Tattered, lesser known movie posters such as ‘Mothra,’ ‘Planet of the Vampires,’ and ‘Attack of the Puppet People’ strewn fervently on brick, graffiti-covered walls provide just a hint of the zany, B-movie glory that opens Lyric Stage Company of Boston’s 45^th season with retro sci-fi musical comedy, ‘Little Shop of Horrors’ continuing through Sunday, October 6 at Lyric Stage in Boston, Massachusetts.  Click here for more information and tickets.

From the inventive special effects to the fascinating, ‘blooming’ set,’ Lyric Stage makes two things abundantly clear:  Don’t feed the plants and everyone’s life should be narrated by a streetwise, Greek chorus.

‘Little Shop of Horrors,’ based on Jack Cullier’s 1932 story Green Thoughts, went on to become a cult classic, featuring actors such as Jack Nicholson, Bill Murray, Rick Moranis, Steve Martin, and John Candy stepping into its various film adaptations.  A remake is in the works as it marks its 60^th anniversary in 2020.

It’s a seemingly simple tale about young love on Skid Rowe in a fledgling flower shop that houses a curious, unique breed of plant.  Some critics have compared it to the daring tone of the cult classic, ‘Rocky Horror Picture Show,’ but ‘Little Shop of Horrors’ offers a more subtle brand of campy charm.

Janie E Howland’s vivid, transformative set is remarkable right down to its carefully timed shop bell.  Not only does it pay homage to vintage films of its time, but ‘Little Shop of Horrors’ is packed with 50s and 60s references such as ‘I Love Lucy,’ Howdy Doody, Donna Reed, and Betty Crocker.

Before going any further, let’s start with that Greek Chorus.  With few exceptions, the music, with lyrics by award-winning composer Alan Menken, have a catchy, rock n roll vibe including tunes that pay tribute to 60s girl groups.  From casual street garments to flashy glam, these three electrifying vocalists certainly know how to make an entrance.  Pier Lamia Porter as Chiffon, Lovely Hoffman as Crystal and Carla Martinez as Ronnette are a tough, humorous, and street-smart trio who unveil the real ins and outs of Skid Rowe through harmony, kicking it off with the catchy signature track, Little Shop of Horrors.

The show has a gift for funny, ironic contrasts with a cast that has increasingly complicated motives.  Wearing black-rimmed glasses, a baseball cap, and fervently wiping his brow, Dan Prior gives real heart to Seymour, a sympathetic, yet conflicted botanist.  With an anxious demeanor and a light city accent, Prior emphasizes Seymour’s inherent, inescapable loneliness as he struggles to remain forthright and honest as the show progresses.  He shines in the darkly tender number Grow for Me and in his awkward adoration for trusting and frequently unlucky Audrey, portrayed wonderfully with plucky charm by Katrina Z Pavao.  In a particularly comical moment, Seymour hopes to take Audrey to “a fancy dinner at Howard Johnson’s.”

Pavao’s lovely soprano vocals carry a lullaby or a soulful belt with equal skill.  She shares her simple, 50s domestic dreams in a funny and tender rendition of Somewhere That’s Green and with Seymour in a powerful rendition of Suddenly Seymour.

Disheveled and desperate in an old cardigan, Remo Airaldi takes on the role of frustrated flower shop owner, Mr. Mushnik.  Having delivered a deliciously dark comedic turn as Ben in Lyric Stage’s ‘The Little Foxes,’ Airaldi once again delivers a dark and memorable performance.  He is especially clever with Dan Prior as Seymour for the manipulative and comical number, Mushnik and Son.

Jeff Marcus brings out his campy, satiric best in several roles including a no-holds-barred performance as Orin, a belligerent, narcissistic biker dentist punctuated with a howling, maniacal laugh.  Marcus and Prior are particularly fun to watch, playing well off each other in the number, Now (It’s Just the Gas). 

However, the real spectacle is  Audrey II, the sly, soulful plant that changes everything.  With versatile and grimly wise vocals by Yewande Odetoyinbo, inventively manipulated by Tim Hoover, and skillfully designed by Cameron McEachern, Audrey II is a comical, extraordinary specimen right down to her bright colors and shiny, dangling teeth.  Audrey II is handled in such an innovative, natural, and majestic way, the results are truly mesmerizing.

Directed and choreographed by Rachel Bertone, Lyric Stage’s ‘Little Shop of Horrors’ continues through October 6 at the Lyric Stage Company of Boston, 140 Clarendon Street in Boston, Massachusetts.  Click here for more information and tickets and here for what is coming up during Lyric Stage’s 45^th season.